If you find a 'Superior' piece of armor with +Enhanced Defense, a Superior Weapon with +Enhanced Damage or a Helm/Weapon that has +Skill bonuses for a certain class, all of these will remain on the final Rune Word that is created. Keep in mind that all Rune Words you create will retain any pre-existing bonuses found on the item. Sorceress' come with Teleport built into their class and Amazons have too slow of frames when casting to make Teleport as useful for them. Some of the builds for these classes are based entirely around Enigma and won't function without it. Necromancers, Paladins, Druids, basically every character except Sorceress' and Amazons will have a build or two that Enigma is the recommended best in slot item for.

It allows me to push more points from strength to vita and it doesn't look like rags off a beggar's back.Enigma is the most popular best in slot Rune Word in the entire game because it is one of the only items that offers the Teleport ability.

I have an old enigma (2nd I ever made) in a mage plate (55 strength requirement) which is absolutely fantastic for a lot of characters with its super-low requirements. Truth is, any armor requiring less than about 80 strength to wear can be a good base for enigma, even a gothic plate and you'll be perfectly fine wearing it in p8 hell. Just think, have you ever heard anyone write 'omg Tal's armor is so bad because it makes my sorc slower' or 'omg if only Tal's armor had 1200 defence rather than 900 it'd be a great armor'? But on enigma suddenly it matters, god knows why. They are also obsessed with rolling perfect defense on their armor, while for nearly every build out there, defense doesn't matter at all. A lot of people are completely obsessed with the frw penalty of heavier armors, while in the game, especially wearing enigma, it's completely unnoticable.

Diablo 2 superior wyrmhide enigma base